Does monistat 1 work reviews? Monistat 1 consists of one dose of 1200 mg of miconazole nitrate and is designed for women who don’t want to wait until bedtime to start treatment. Amazoncom Monistat 1-day Yeast Infection Treatment Ovule Itch Cream Combination Pack And Monistat 7-day Yeast Infection Treatment Cream External Itch Relief Cream Everything Else The 1day works too, but it still takes about a week to kick. Does monistat 1 work in one day . This medication is used to treat vaginal yeast infections. It works by stopping the growth of yeast (fungus) that causes the infection. That happened to me before and it was a bacterial infection. Tioconazole ointment reduces vaginal burning, itching, and discharge that may occur with this condition. In even though it was just dose. The 3 day treatment usually isnt long enough to completely eradicate the infection. While monistat 1 products offer the most time convenient yeast infection treatment course, most women do no...