Topical finasteride provides localised treatment for hair loss, without taking the treatment systemically (i.e. To enhance its effectiveness, topical finasteride can be compounded with minoxidil (e.g. Topical Finasteride For Hair Growth - Men And Women Hair Loss How long does it take for finasteride to work? How long for topical finasteride to work . Topical finasteride mixed with minoxidil is powerful enough to maintain the result of oral finasteride, when the oral is discontinued. Finasteride is to be taken by mouth for up to three months before seeing a benefit from the medication. If finasteride will not work for you within 12 months of use, do not continue with the treatment because it will no longer benefit you. The timeline may vary for some people, but an overdose isn't required or recommended in. 8 rows assessing systemic pharmacodynamics of topical finasteride. For hair growth, it can take three to four months before the medication begins to affect. ...