We only use a tiny amount of botox to improve these lines. Botox does not work to make the lips more plump, but to reduce fine lines around the lips and, in selected patients, to slightly lift the middle portion of the lip. How Long Does Botox Take To Work Botox Botox Injections Botox Cosmetic This enhances the upper lip appearance and your confidence. How long does it take for botox to work on lips . The botox lip flip keeps the upper lip from thinning, or 'disappearing' when you smile, and can also prevent excess teeth [showing], or the 'gummy smile', jessie cheung, md shares. You need to be aware you will possibly have a little diminished movement in the lips. Botox does not work to make the lips more plump. It can minimize lines around the corner and help elevate those corners. How long for botox to work. But it’s all quite subtle. Usually the botox is used in combination with lip fillers and it is the filler that does most of the work in fl...